Expression of S100A8 correlates with inflammatory lung disease in congenic mice deficient of the cystic fibrosis transmembrane conductance regulator

Abstract Background Lung disease in cystic fibrosis (CF) patients is dominated by chronic inflammation with an early and inappropriate influx of neutrophils causing airway destruction.Congenic C57BL/6 CF mice develop lung inflammatory disease similar to that of patients.In contrast, lungs of congenic BALB/c CF mice remain unaffected.The basis of th

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Understanding the emerging potential of synthetic biology for food science: Achievements, applications and safety considerations

The advent of the first synthetic cell has triggered significant interest in synthetic biology research and its potential impact on various fields, including industry, agriculture, health, and the environment.With its unique blend of molecular biology, genetics, engineering, and computational modeling, synthetic biology is becoming a crucial tool i

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